A Paradigm Shift to Prevent and Treat Alzheimer's Disease: by Howard Friel,Sally A. Frautschy

By Howard Friel,Sally A. Frautschy

A Paradigm Shift to avoid and deal with Alzheimer’s sickness: From Monotargeting prescribed drugs to Pleiotropic Plant Polyphenols is the 1st publication to systematically convey the strong pleiotropic pharmacological results on Alzheimer’s disorder of plant-based compounds from historic meals that people were eating properly with vast well-being merits for millions of years.

These plant-based compounds contain curcuminoids from turmeric, resveratrol from pink wine and grape seed extract from different grape items, epigallocatechin-gallate (EGCG) from eco-friendly tea, and oleocanthal and oleuropein from olive oil, as well as a different extract, EGb 761, from the leaves of Ginkgo biloba, the oldest residing species of tree in the world.

This booklet additionally provides a brand new analytical framework that convincingly favors a multi-targeting ("pleiotropic") method of the prevention and therapy of advanced continual ailments, unlike the mono-targeting of the pharmaceutical version.

A Paradigm Shift to avoid and deal with Alzheimer’s sickness is a special and intriguing source for pharmaceutical scientists, pharmacologists, neurologists, normal practitioners, examine scientists in numerous scientific and existence sciences, healthcare pros in scientific and govt positions, traditional scientific colleges, colleges of naturopathic drugs, healthcare and clinical reporters, executives in either nationwide public healthcare platforms and personal insurers, and expert basic readers.

  • Presents conscientiously compiled proof aiding the necessity to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic focusing on for the prevention and therapy of Alzheimer’s disease
  • Includes invaluable tables that combination pleiotropic pharmacological results of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks
  • Highlights regulatory features and discusses the demanding situations and power strategies with admire to bioavailability of yes plant polyphenols

Show description

Read or Download A Paradigm Shift to Prevent and Treat Alzheimer's Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols PDF

Best biochemistry books

Vascular Biochemistry (Developments in Molecular and Cellular Biochemistry)

This quantity explores all facets of vascular biochemistry and comprises chapters that supply an knowing of vascular functionality with descriptions of tissue parts found in the vascular wall in addition to an exploration of the hemodynamic and metabolic actions linked to this functionality. additionally, a few chapters discover the vasculature less than stipulations which mimic numerous sickness states.

Glycobiology and Medicine: Proceedings of the Sixth Jenner Glycobiology and Medicine Symposium, 14-17 September, 2002, Seillac, France (Advances in Experimental Medicine and Biology)

This booklet comprises the court cases of the 6th Jenner Glycobiology and drugs Symposium, held 14-17 September, 2002, in Seillac, France. This publication highlights the newest advancements in glycoimmunology, together with glycosylation-dependent bacterial and viral infections, lectin and proteoglycan-dependent interactions in leukocyte homing techniques to lymphoid tissues and infected tissues, congenital defects in glycosylation of glycoproteins and glycolipids, and the position of carbohydrates in tumour improvement and neuropathology, together with Creutzfeldt-Jakob disorder.

G Protein-Coupled Receptors - Modeling and Simulation: 796 (Advances in Experimental Medicine and Biology)

G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and finally into organic responses. due to the fact that GPCRs are typical pursuits for roughly forty% of all glossy drugs, it isn't amazing that they've been the topic of severe examine.

Global Food Security and Wellness

This e-book relies on chosen papers from keynote and symposium periods given on the sixteenth overseas Union of meals technology and know-how (IUFoST) international Congress, held in Foz do Iguaçu, Brazil August, 2012. The subject of the Congress was once the demanding situations confronted via meals technology in either the constructed and constructing areas of the realm.

Extra info for A Paradigm Shift to Prevent and Treat Alzheimer's Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols

Sample text

Download PDF sample

Rated 4.75 of 5 – based on 41 votes